At Oklahoma Cancer Specialists and Research Institute and St. John Health System, we understand that every cancer journey is different, so we develop specialized treatment plans to meet patients' unique needs. We offer a variety of treatment options, including chemotherapy, radiation therapy, biological therapy and surgical procedures.

Together, Oklahoma Cancer Specialists and St. John offer the latest tools and technologies, such as CyberKnife, Elekta and TomoTherapy. Diagnostic services include MRI, CT and PET, as well as ultrasound, interventional radiology and mammography. And because we believe in healing for the whole person — mind, body and spirit — our medical treatment is combined with support services like physical therapy, nutrition counseling and palliative care.

Cancers we treat

  • Bladder
  • Blood (hematologic disorders)
  • Bone
  • Brain
  • Breast
  • Cervical
  • Colorectal (colon and rectum)
  • Digestive system
  • Head and neck
  • Kidney
  • Leukemia
  • Lung
  • Lymphoma
  • Multiple myeloma
  • Neuroendocrine tumors
  • Oral cavity
  • Ovarian
  • Prostate
  • Skin (including melanoma)

Learn more about the state-of-the-art treatment options available to you at Oklahoma Cancer Specialists and St. John:

Advanced Technology

St. John and Oklahoma Cancer Specialists and Research Institute utilize the latest technology in cancer treatment, including CyberKnife, Elekta, TomoTherapy and linear accelerators. Learn More

Breast Center

Since 1974, the St. John Breast Center has provided women with hope. While breast cancer can be deadly, it can be cured if found and treated early. St. John was the first in Tulsa to offer all-digital mammography. Learn More

Clinical Research

The clinical research department at Oklahoma Cancer Specialists coordinates and conducts trials to help determine the safety and effectiveness of devices, diagnostic products, medications and treatment regimens intended for patient use. Learn More

CyberKnife Center

The CyberKnife Robotic Radiosurgery System is a revolutionary advancement in non-invasive cancer treatment technology. CyberKnife directs focused radiation to benign and malignant tumors. Learn More


St. John Hospice provides medical care and pain management for patients with limited life expectancy, as well as emotional and spiritual support for their loved ones. Learn More

Palliative Care

Palliative care is special support given to patients and the families of patients who suffer from a chronic or life-threatening illness. Comfort and quality of life are key aspects of this care. Learn More

Survivor Rehabilitation

The cancer survivor rehabilitation program at St. John Medical Center offers premium, insurance-covered therapy services specifically designed for people undergoing cancer treatment or living with its aftermath. Learn More